Creamy Spinach Chicken Casserole – Easy, Cheesy, and Perfect for Weeknights

If you’re looking for the ultimate comfort food, this Creamy Spinach Chicken Casserole is a dish that delivers flavor, richness, and simplicity in one baked pan. It’s cozy, family-friendly, and combines tender chicken, melty cheese, and nutritious spinach, perfect for weeknights, meal prep, or even a casual dinner party.

This casserole not only satisfies cravings but also offers nutritional benefits thanks to key ingredients like spinach and lean chicken. You can even explore similar indulgent options like this million dollar chicken casserole if you’re craving something even richer!

Not sure about your prep methods? Here’s a helpful guide on whether it’s safe to put raw chicken in a casserole to make sure your dish is both safe and satisfying.

Why You’ll Love This Creamy Spinach Chicken Casserole

• Quick & easy to assemble, minimal prep
• Uses simple, everyday ingredients
• Perfect for meal prep and leftovers
• Can be made low-carb or gluten-free
• Kids and picky eaters love it

Ingredients Nedeed For Creamy Spinach Chicken Casserole

Here’s what you’ll need:

Main Ingredients

• 2 cups cooked chicken (breasts or thighs), shredded or cubed
• 3 cups fresh spinach (or 1½ cups frozen spinach, thawed and drained)
• 1 cup cream cheese (softened)
• ½ cup sour cream or Greek yogurt
• ¾ cup shredded mozzarella cheese
• ¼ cup Parmesan cheese
• 2 cloves garlic, minced
• Salt and pepper to taste

Optional Add-ins

• Sautéed mushrooms
• Artichoke hearts
• Red pepper flakes for heat

How to Make This Creamy Spinach Chicken Casserole

1. Preheat and Prep

• Preheat oven to 375°F (190°C)
• Grease a 9×13-inch casserole dish

2. Cook the Spinach

• If using fresh spinach, sauté in olive oil until wilted
• If using frozen, thaw and squeeze out all excess moisture

3. Make the Creamy Base

In a large mixing bowl, combine:

• Cream cheese
• Sour cream or Greek yogurt
• Minced garlic
• Salt and pepper

Mix until smooth.

4. Add the Chicken and Spinach

• Stir in the shredded chicken and spinach until everything is coated in the creamy mixture

5. Layer and Bake

• Pour mixture into the casserole dish
• Sprinkle mozzarella and Parmesan over the top
• Bake uncovered for 25–30 minutes or until bubbly and golden

Not sure if you should cover it? Here’s a guide on should chicken casserole be covered when baking

Pro Tips for the Best Casserole

• Use rotisserie chicken to save time
• Drain spinach thoroughly to avoid a watery casserole
• Add a touch of nutmeg to enhance the creamy flavor
• Want more texture? Sprinkle crushed Ritz crackers or panko on top before baking
• Need something even cheesier? Try blending in flavors from this creamy Asiago chicken dish.

Storage & Reheating

Fridge

• Store leftovers in an airtight container for up to 4 days

Freezer

• Freeze before or after baking for up to 2 months
• Wrap tightly with foil and place in a freezer bag

Reheat

• Bake at 350°F for 15–20 minutes
• Microwave in 1-minute intervals until hot

Variations and Add-Ons

Customize this casserole to suit any diet or flavor preference:

Low-Carb / Keto

• Skip breadcrumbs or crackers
• Use full-fat cream cheese and mozzarella

Gluten-Free

• Use gluten-free cream cheese and toppings
• Avoid any flour-thickened sauces

Additions

• Pasta for a fuller meal
• Cauliflower rice for low-carb twist
• Hot sauce for spice lovers

What to Serve With It

Make it a complete meal with any of the following:

• Garlic bread or crusty rolls
• Side salad with vinaigrette
• Roasted vegetables
• Cauliflower mash or zoodles

Nutritional Information (Per Serving Estimate)

• Calories: 350–400
• Protein: 28g
• Fat: 22g
• Carbs: 8–10g (lower if keto version)
• Note: Numbers vary based on ingredients used

Make-Ahead & Freezer Tips

• Assemble and refrigerate overnight before baking
• Freeze before baking for future easy meals
• Label with name/date for freezer tracking

Common Mistakes to Avoid

• Overcooking chicken, use pre-cooked or rotisserie for consistency
• Not draining spinach enough, this leads to soggy texture
• Forgetting to season, salt, pepper, garlic = flavor!
• Baking uncovered for too long, top may burn

FAQ About Creamy Spinach Chicken Casserole

Final Thoughts

The Creamy Spinach Chicken Casserole is a total weeknight winner. Whether you’re feeding a crowd, doing meal prep, or just want a cozy dinner, this dish is packed with rich flavor, protein, and veggie goodness. It’s endlessly customizable, easy to make, and so satisfying.

Creamy Spinach Chicken Casserole – Easy, Cheesy, and Perfect for Weeknights

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• Author: MERIEM
• Total Time: 45 minutes
• Yield: 6 servings 1x
• Diet: Low Calorie

Print Recipe

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Description

A rich and comforting creamy spinach chicken casserole made with tender chicken, sautéed spinach, and a cheesy cream sauce. Perfect for a cozy family dinner, meal prep, or freezer-friendly meals.

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Ingredients

Scale 1x2x3x

2 cups cooked shredded chicken (breast or thighs)
3 cups fresh spinach (or 1½ cups frozen, thawed and drained)
1 cup cream cheese (softened)
½ cup sour cream or Greek yogurt
¾ cup shredded mozzarella cheese
¼ cup grated Parmesan cheese
2 cloves garlic (minced)
½ teaspoon salt
¼ teaspoon black pepper
Optional: ½ cup cooked bacon bits, ½ cup sautéed mushrooms, ½ teaspoon red pepper flakes

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Instructions

Preheat oven to 375°F (190°C) and grease a 9×13-inch baking dish.
Sauté spinach in a pan until wilted or drain thawed frozen spinach well.
In a large bowl, mix cream cheese, sour cream, garlic, salt, and pepper until smooth.
Fold in the cooked chicken and spinach.
Transfer the mixture to the baking dish and spread evenly.
Top with mozzarella and Parmesan cheese.
Bake uncovered for 25–30 minutes until bubbly and golden brown on top.
Garnish with fresh parsley if desired.
Let cool slightly before serving.

Notes

Use rotisserie chicken to save time.
Make it low-carb by skipping any breadcrumb topping.
Drain spinach thoroughly to prevent a watery casserole.
You can prepare it a day in advance and bake later.
Freezes well before or after baking.

• Prep Time: 15 minutes
• Cook Time: 30 minutes
• Category: Dinner
• Method: Baking
• Cuisine: American

Nutrition

• Serving Size: 1 serving
• Calories: 390
• Sugar: 2g
• Sodium: 520mg
• Fat: 26g
• Saturated Fat: 12g
• Unsaturated Fat: 11g
• Trans Fat: 0g
• Carbohydrates: 7g
• Fiber: 1g
• Protein: 28g
• Cholesterol: 95mg

Keywords: Creamy spinach chicken casserole, cheesy chicken bake, low carb casserole, spinach and chicken recipe